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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
GOT1L1
All Species:
4.55
Human Site:
S61
Identified Species:
8.33
UniProt:
Q8NHS2
Number Species:
12
Phosphosite Substitution
Charge Score:
0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8NHS2
NP_689626.2
421
47305
S61
Q
K
T
R
L
Q
I
S
Q
D
P
S
L
N
Y
Chimpanzee
Pan troglodytes
A5A6K8
413
46215
A62
K
K
V
E
Q
K
I
A
N
D
N
S
L
N
H
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_532809
406
45869
S61
P
K
I
R
L
Q
I
S
Q
D
P
S
L
N
Y
Cat
Felis silvestris
Mouse
Mus musculus
Q7TSV6
404
45439
A61
H
K
T
R
L
Q
I
A
E
D
P
S
L
D
Y
Rat
Rattus norvegicus
P13221
413
46410
A62
R
K
V
E
Q
K
I
A
N
D
H
S
L
N
H
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001507985
380
42638
E58
L
P
V
V
K
K
V
E
Q
R
I
A
G
D
N
Chicken
Gallus gallus
P00504
412
45917
A61
R
K
V
E
Q
L
I
A
G
D
G
S
L
N
H
Frog
Xenopus laevis
NP_001080543
411
46052
N63
E
Q
M
I
A
N
D
N
S
L
N
H
E
Y
L
Zebra Danio
Brachydanio rerio
NP_998222
410
45964
R78
I
L
G
L
P
E
F
R
S
S
A
S
K
I
A
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_725534
437
48561
A80
R
K
T
E
I
S
I
A
S
D
E
Q
V
N
H
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q22067
408
45475
T62
E
V
E
I
A
N
D
T
S
L
N
H
E
Y
L
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
P46645
405
44248
D62
A
E
Q
Q
L
V
N
D
P
S
R
V
K
E
Y
Baker's Yeast
Sacchar. cerevisiae
P23542
418
46039
H61
K
A
A
E
K
L
I
H
N
D
S
S
Y
N
H
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
39.9
N.A.
76.7
N.A.
71.5
39.4
N.A.
33.9
37.7
37.7
39.6
N.A.
35.7
N.A.
35.3
N.A.
Protein Similarity:
100
57.9
N.A.
85.5
N.A.
81.7
57.7
N.A.
51.7
58.1
56.5
58.6
N.A.
52.4
N.A.
54.3
N.A.
P-Site Identity:
100
40
N.A.
86.6
N.A.
73.3
40
N.A.
6.6
40
0
6.6
N.A.
33.3
N.A.
0
N.A.
P-Site Similarity:
100
66.6
N.A.
86.6
N.A.
93.3
66.6
N.A.
33.3
60
20
13.3
N.A.
66.6
N.A.
13.3
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
30.8
27.5
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
51.5
46.5
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
13.3
26.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
26.6
40
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
8
8
0
16
0
0
39
0
0
8
8
0
0
8
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
16
8
0
62
0
0
0
16
0
% D
% Glu:
16
8
8
39
0
8
0
8
8
0
8
0
16
8
0
% E
% Phe:
0
0
0
0
0
0
8
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
8
0
0
0
0
0
8
0
8
0
8
0
0
% G
% His:
8
0
0
0
0
0
0
8
0
0
8
16
0
0
39
% H
% Ile:
8
0
8
16
8
0
62
0
0
0
8
0
0
8
0
% I
% Lys:
16
54
0
0
16
24
0
0
0
0
0
0
16
0
0
% K
% Leu:
8
8
0
8
31
16
0
0
0
16
0
0
47
0
16
% L
% Met:
0
0
8
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
16
8
8
24
0
24
0
0
54
8
% N
% Pro:
8
8
0
0
8
0
0
0
8
0
24
0
0
0
0
% P
% Gln:
8
8
8
8
24
24
0
0
24
0
0
8
0
0
0
% Q
% Arg:
24
0
0
24
0
0
0
8
0
8
8
0
0
0
0
% R
% Ser:
0
0
0
0
0
8
0
16
31
16
8
62
0
0
0
% S
% Thr:
0
0
24
0
0
0
0
8
0
0
0
0
0
0
0
% T
% Val:
0
8
31
8
0
8
8
0
0
0
0
8
8
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
8
16
31
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _